Ying Xian, M.D., Ph.D., FAHA, is a tenured Associate Professor in the Department of Neurology, with a secondary appointment in the Department of Population and Data Science at UT Southwestern Medical Center.

Dr. Xian earned his medical degree at Beijing Medical University (Peking University Health Science Center), completed a residency in Internal Medicine, and a fellowship in Cardiology at Peking University People’s Hospital, and Fuwai Hospital, Peking Union Medical College. Dr. Xian obtained his Ph.D. degree in Health Services Research and Policy at University of Rochester and received the American Heart Association/American Stroke Association (AHA/ASA) Pharmaceutical Roundtable-Spina Fellowship training in Cardiovascular Outcomes Research at Duke University. 

For more than a decade, Dr. Xian’s research has been focused on improving health care quality and outcomes in patients with cardiovascular disease and stroke. Prior to joining the UT Southwestern faculty in 2021, Dr. Xian served as the clinical lead for the AHA/ASA Get With The Guidelines Stroke (GWTG-Stroke) Registry and Society of Thoracic Surgeons' (STS) National Database Analytical Center at Duke. He has led multiple groundbreaking comparative effectiveness and patient-centered outcomes research projects, with extensive experiences with large national registry and data linkage with Medicare claims.

Dr. Xian is the principle investigator of two National Institute on Aging (NIA) funded R01s to evaluate the safety and efficacy of antithrombotic therapy for secondary stroke prevention and the AHA Clinical Research Program and Scientist Development Grant to investigate off-label/off-guideline thrombolytic therapy in stroke. Dr. Xian has served on multiple committees of the AHA/ASA, including the GWTG Quality Improvement Subcommittee, Stroke Systems of Care Advisory Group, Stroke Council’s Quality and Outcomes Committee, Quality of Care and Outcomes Research (QCOR) Council’s Young Clinicians & Investigators Committee, and GWTG-Stroke Clinical Work Group. Dr. Xian has authored or coauthored over 200 peer-reviewed publications and has been recognized for his research through the AHA QCOR Young Investigator Award and the Northwestern Junior Faculty Clinical Research Award.

Research Interest

  • Cardiovascular disease
  • Cognitive impairment and dementia
  • Comparative effectiveness research
  • Global health
  • Health services research
  • Outcomes research
  • Patient-centered outcomes research
  • Primary and secondary prevention
  • Quality improvement
  • Stroke


Featured Publications LegendFeatured Publications


Featured Books Legend Featured Books

Data Resources. In Understanding Clinical Research

Renato Lopes and Robert Harrington (2013). McGraw-Hill Education / Medical

Honors & Awards

  • 2nd Place Winner, Junior Faculty Clinical Category Young Investigator Research Award
    12th Annual Northwestern Cardiovascular Young Investigators' Forum (2016)
  • Fellow
    American Heart Association (2016)
  • Travel Award
    International Stroke Conference (2016)
  • Distinguished Clinical Research Achievement Award
    Clinical Research Forum. Fonarow GC, Zhao X, Smith EE, Saver JL, Reeves MJ, Bhatt DL, Xian Y, Hernandez AF, Peterson ED, and Schwamm LH. Door-to-needle times for tissue plasminogen activator administration and clinical outcomes in acute ischemic stroke before and after a quality improvement initiative. JAMA. 2014, 311(16), 1632-1640 (2015)
  • 2nd Place Winner, Junior Faculty Clinical Track
    10th Annual Northwestern Cardiovascular Young Investigators' Forum (2014)
  • Young Investigator Finalist
    American Heart Association Epidemiology and Prevention|Nutrition, Physical Activity and Metabolism Scientific Sessions (2011)
  • Young Investigator Award
    American Heart Association Quality of Care and Outcomes Research Interdisciplinary Council (2010)
  • Bertram Scott Research Fellow
    American Heart Association Founders Affiliate (2008)
  • Predoctoral Fellowship
    American Heart Association Founders Affiliate (2008)
  • Excellus Fellowship in Health Services Research and Policy
    Excellus BCBS (2005)
  • Dean's Fellowship
    University of Rochester (2003)

Professional Associations/Affiliations

  • African Stroke Organization (2021)
  • Gerontological Society of America (2021)
  • European Stroke Organisation (2019)
  • World Stroke Organization (2019)
  • American Heart Association (2007)